Endocrine pancreas consists of Islets of Langerhans (1 to 2 million).
Types of cells present in Islets of Langerhans – alfa cells (glucagon) and beta cells (insulin).
Glucagon is a peptide hormone which plays an important role in maintaining normal blood glucose level. It acts on liver cells and stimulates glycogenolysis resulting in increased blood sugar.
Insulin is a also a peptide hormone which play an important role in regulation of glucose homeostasis. It acts on hepatocytes and adipocytes and enhances cellular glucose uptake and utilization. It also stimulates conversion of glucose to glycogen.