The respiratory balance sheet
- The net gain of ATP for every glucose molecule oxidised can be calculated based on the following assumptions:
- There is a sequential, orderly pathway functioning, with one substrate forming the next and with glycolysis, TCA cycle and ETS pathway following one after another.
- The NADH synthesised in glycolysis is transferred into the mitochondria and undergoes oxidative phosphorylation.
- None of the intermediates in the pathway are utilised to synthesise any other compound.
- Only glucose is being respired.
- There can be a net gain of 36 ATP molecules during aerobic respiration of one molecule of glucose.
Fig. Respiratory balance sheet