Class 11 Biology Respiration In Plants Amphibolic pathway

Amphibolic pathway

  • Amphibolic pathway is the one which involves both anabolism and catabolism.
  • Krebs cycle is a classic example of amphibolic pathway.
  • Krebs cycle involves both the catabolism of carbohydrates and fatty acids and the anabolism of amino acids.
  • Fats should be broken into glycerol and fatty acid, and if fatty acids were to be respired they would first be degraded to acetyl CoA and enter the pathway after being converted to PGAL.
  • Glycerol enter the pathway after it is converted to PGAL.
  • The proteins would be degraded by proteases and the individual amino acids depending on their structure would enter the pathway at some stage within the Krebs cycle.
  • Fatty acids would be broken down to acetyl CoA before entering the respiratory pathway when it is used as a substrate.
  • But when the organism needs to synthesize fatty acids, acetyl CoA would be withdrawn from the respiratory pathway for it.
  • Respiratory pathway can be seen during both breakdown and synthesis of fatty acids.


Fig. Amphibolic pathway

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