Class 12 Biology Inheritance Variation LINKAGE AND RECOMBINATION


  • Morgan carried out several dihybrid crosses in Drosophila to study genes that were sex-linked.
  • Morgan hybridized yellow-bodied, white-eyed females to brown-bodied, red-eyed males and intercrossed those F1
  • According to him, two genes did not segregate independent of each other and F2 ratio deviated from 9:3:3:1. This concluded that genes are linked. This process is called linkage.
  • Recombination is the rearrangement of genetic material. The generation of non-parental gene combination during dihybrid cross is called recombination. When genes are located on same chromosome, they are tightly linked and show less linkage. This is responsible for variation.

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