Class 12 Biology Molecular Basis of Inheritance Biochemical nature of Transforming Principle

Biochemical nature of Transforming Principle

Bacteriologists performed a series of experiments to identify the Transforming  Principle.

 

  • Transforming principle precipitated with alcohol. This showed it was not Carbohydrate.
  • Transforming principle could not be destroyed with Proteases. Thus, it was not Protein.
  • Transforming principle could not be destroyed with Lipases. This proved it was neither Lipids.
  • Transforming principle could not be inactivated with Ribonuclease, hence not RNA.
  • Transforming principle could be inactivated with Deoxyribonuclease.

Class_12_Molecular_Basis_Of_Inheritance_Transforming_DNA                     

Transforming principle was DNA. Therefore, DNA was the genetic material.

 

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